PHGY 214 Lecture Notes - Lecture 1: Monocyte, Neurohormone, Multiple Sclerosis

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12 May 2016
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* the ability of an organism to regulate its internal conditions. * systems transfer material from the external environment to the internal. rials are mixed and exchanged between the plasma and interstitial fluid. cells, in turn, pick these up. Factors homeostatically regulated: concentration of nutrient molecules, concentration of oxygen and carbon dioxide, concentration of waste product, ph, temperature, osmolarity. To maintain homeostasis you need a homeostatic control system, which . Detects deviations from the normal internal environment. Triggers the needed adjustments for restoring the factor within the normal range (effector) Intrinsic control - built into/inherent in an organ (self-serving) Extrinsic control - regulatory mechanisms initiated outside an organ to alter the activity of an organ (synchronized regulation of several organs towards a goal) Set control - desired value of controlled variable. Sensor - detects any change in controlled variable. Feedback loops - the key to homeostasis where the effector opposes change to set point.

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