PHAR 340 Lecture Notes - Lecture 20: Latrotoxin, Carotid Sinus, Synaptic Vesicle
25 Oct 2017
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Recap of lec 1: an autonomic homeostatic reflex. Baroreceptor re ex: a mechanism for moment to moment arterial blood pressure control. > by activation of stretch receptors located in the walls of most large arteries. > in the wall of each internal carotid artery just above the carotid bifurcation (ie: carotid sinus) and in the wall of the aortic arch. Autonomic neurotransmission: nerve impulse, membrane depolarization, calcium entry, synaptic vesicle exocytosis. Week 7 lec 2: diffusion of nt across neuroeffector junction, activation of nt receptors, depolarization of postganglionic neuron or response to effector cell. Receptor antagonists : i think this list is all receptor antagonists. There are two types : nicotinic receptors and muscarinic receptors. Nn : pre- post ganglionic neurons transmission to adrenal medulla (gaglionic) M3: endothelium, smooth muscle, glands so m1: brain (brain and spinal cord make up cns and neutrons that are autonomic and post-ganglionic)
