PHAR 100 Lecture Notes - Lecture 29: Blood Doping, Perjury, Erythropoietin

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List five major classes of drugs abused by athletes. Explain the rationale for banning performance-enhancing drugs by most sports associations. Describe the mechanism of action and effect on performance of the major classes of drugs abused by athletes. List the potential toxicities of the performance-enhancing substances used by athletes. History and legend says that ancient greeks used mushrooms to increase performance. Legend says that aztec people ate human heart sacrifices to improve performance. Early belgian racers used sugar cubes dipped in ether. In the early 1900"s boxers ingested brandy and cocaine. Other drugs used at the number were caffeine, alcohol, nitroglycerin, ethyl either, strychnine, and opium. Amphetamines and anabolic steroids started being used in the 1950"s and were quickly banned. First steroid tests happened in the 1976 montreal olympic games. Surprise testing at the 1983 pan am games caused people to drop out. Canadian ben johnson was stripped of his 1988 gold medal after a positive steroid test.

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