PHAR 100 Lecture Notes - Lecture 24: Vitamin D Deficiency, Neural Tube Defect, Linus Pauling
Document Summary
Definition: substance required for maintenance of normal function but must be provided from external sources; not made in the body. Often found by studying vitamin deficiencies: ie) b1 polyneuritis, b12 pernicious anemia. Can be fat soluble (a, d, e and k) or water soluble (c and b). When taken as tablets they are considered drugs, when taken in food not. Ear estimated average requirement: meets the category for 50 % of people in any one category (age, sex etc. ) Rda recommended dietary allowance: daily intake required to meet the needs of 97 98 % of healthy individuals in one group (age, sex etc) Ai adequate intake: recommended daily amount based on observed or scientific data for specific groups of individuals. Ul highest daily intake that is likely to pose no adverse health effects to almost all individuals. *disturbances on absorption ie) prolonged diarrhea, liver/ gi diseases, antibiotics. *increased tissue requirements ie) pregnancy, disease states, stress, hard work.