MICR 221 Lecture Notes - Lecture 1: Diphtheria Toxin, Archaea, Green Fluorescent Protein
Document Summary
Napolean: defeat in 1813 after allies at leipziq were ill. Cholera: outbreak in haiti brought by un peacekeepers after earthquake in. Discovered microbial world + spermatozoa, rbc, major microbes, called bacteria wee animalcules. Refused to sell microscope or show ppl how to make them. Hooke published 1st pic of microbe but work was not acknowledged bc no one spoke deutch. Helmont: rags and cheese will spon turn into mice. Redi: took 3 pieces of meat, left one open, one w cork and one covered w gauz, maggots were on meat, not at all or on gauz respectively. Spallanzani: put beef broth in flask and boiled while sealed. Pasteur: swan neck flask, flask was not sealed like spallanzanerei but long neck kept microbes out therefore spont generation not possible. 1st use of quarantine and germ warfare, 1/3 of european pop killed, eventually killed 80% of pop. Sars is similar yet only 774 ppl died, w 8000 cases.