ENSC 201 Lecture Notes - Lecture 16: Clostridium, Blood Lead Level, Smog
11 Apr 2017
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Document Summary
Vulnerable populations: include the economically disadvantaged, racial and ethnic minorities, the uninsured, low-income children, the elderly, the homeless, those with. Susceptible and vulnerable populations susceptible and vulnerable populations require special consideration. May warrant separate risk assessments under certain circumstances. Wide difference in metabolism of xenobiotics: absorption, distribution to different organs, excretion, metabolism, we have to account for these differences to find what is safe blood brain barrier is more permeable in infants immature organs. Child specific behaviour children live, learn and pay in different physical environments than adults (spend time outside a lot more) Knowledge gaps exposures are very variable-estimated retrospectively but we know they exist, we just don"t know their full effects. Metabolism changes significantly during pregnancy - adds complexity: changes vary between women which changes exposure to fetus children are not mini-adults" and can"t assume they will act the same as adults.
