BIOL 200 Lecture Notes - Lecture 11: Endoplasmic Reticulum, Nuclear Membrane, Cytoskeleton

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Module vii: internal cell structures: endomembrane systems and cytoskeleton. Internal cellular structures: (cid:862)the big three(cid:863) (cid:449)e ha(cid:448)e see(cid:374) already, nucleus, mitochondria. Chloroplasts: endomembrane structures, endoplasmic reticulum and golgi complex, membrane-bound organelles, peroxisomes, lysosomes, vacuoles, vesicles, thi(cid:374)k (cid:862)organization and compartmentalization(cid:863, cytoskeleton structures, made of proteins, fibrous (linear) structures. Intermediate filaments: microtubules, actin filaments, thi(cid:374)k (cid:862)organization, framework and movement(cid:863) Key internal membranes: most cells have a set of organelles, different cells have different specialization, endomembranes: er. Found in large quantities in liver (hepatocytes) Detoxify non-water soluble drugs and chemicals such as metabolites that would accumulate in membranes: calcium pumping, rough er. Packaging for transport to golgi or cell membrane: site of er membrane phospholipid assembly, golgi complex. Function: protein processing and delivery, proteins in vesicles from er are further modified ex. glycosylated proteins may have sugars synthesized or modified, macromolecule synthesis. Import/export (endocytosis and exocytosis: from cell membrane (import)

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