NURS 3014 Lecture Notes - Lecture 14: Idiopathy, Comorbidity, Physical Therapy

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Osteoarthritis: osteoarthritis (oa) aka degenerative joint disease (djd, disorder characterized by progressive deterioration of the articular cartilage, systemic inflammation and involvement is not typical (inflammation is localized. Inflammatory joint disease impairs blood flow: neuropathic diseases (peripheral neuropathies, repetitive injury (e. g. , athletic injuries who sustain injuries, computer typing and carpal tunnel, knitting, more common in men than women. ** note that the distinction between primary and secondary oa is not always clear. ** the resulting damage creates a cycle, triggering the chondrocyte response -> release of cytokines : chondrocyte cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. The matrix is the lake" in which chondrocytes swim: the cartilage and bone beneath the cartilage erode and osteophytes (bony spurs) form, resulting in narrowed joint spaces. Risk factors: risk factors for oa include:

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