NURSING 2PF3 Lecture Notes - Lecture 12: Tumor Suppressor Gene, G1 Phase, G0 Phase
11 Apr 2018
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Document Summary
Uncontrolled growth of abnormal cells in the body; term is used interchangeably with the malignant or malignancy. Malignant or cancerous cells are composed of less well-differentiated cells that have lost the ability to control both cell proliferation and differentiation into a mature cell. Leading cause of death worldwide 8. 2 million deaths. In canada cancer accounts for 0% of deaths 42% of females and 45% of males will develop cancer in their lifetimes; 2/5 canadians will develop cancer in their lifetime; 1/4 canadians will die from cancer. Cancer increases with age; 70 years of age and older. Rates of death vary due to variation in cancer screening and treatment. Lung, prostate, breast, and colorectal cancer are the 4 most common. Lung cancer is the leading cause of death from cancer; 50% of all cancer deaths. All cells progress through 5 phases: g0, g1, s, g2 and m.
