KINESIOL 3U03 Lecture 2: KIN 3U03 march 15th
22 Feb 2019
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Document Summary
Gonadotrophin-releasing hormone send lhrh/fshrh to pituitary => stimulate lh/fsh release => result increasing release of testosterone/estrogen: testosterone/estrogen: negative feedback loop. Fsh levels in childhood => females level 2x higher than males. Higher level in infant girls (but reduce at pre-puberty level) At puberty => females increase 3x; males increase 6x in adulthood => remain high in both genders: at menopause => females have dramatic increase (10x); late 40s - early 50s. Lh levels variable to age 1 (not really a pattern) -> might due to studies are hard to run in children similar level in both gender until puberty start. Early adulthood => females and males increase to similar level. Sex steroids (gender specific) => testosterone + estradiol. Synthesized in testes, ovaries, adrenal cortex and conversion of steroid precursors => some are converted from adipose tissue. Most abundant male androgen comes from cholesterol precursors (testes/adrenal cortex) testosterone converted to dihydrotestosterone in peripheral tissue: testosterone"s major target = muscle, bone.
