KINESIOL 1Y03 Lecture Notes - Lecture 11: Dermis, Orthostatic Hypotension, Sepsis
31 Jul 2018
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Extend beyond boundary of original wound but has excess tissue amount (in comparison to what is actually needed to replace damaged dermis) 01. 02. 01 cerebral vascular accident/transient ischemic attack stroke. Risk factors: non modifiable age (doubles after 55 yrs), m>f, fmhx, previous stroke or tia, modifiable htn, cardiac disease, diabetes, cholesterol, smoking, obesity, cocaine/meth use, oral contraceptives (?) Ischemic stroke (80%) caused by thrombosis, embolic, lacunar infarct (in deep area of the brain, related to diabetes and htn) A) death of tissue where there is no blood (core death) B) possible preservation of area surrounding core that is supplied by collaterals (ischemic penumbra) * cerebellum and hippocampus neurons ++ sensitive to ischemia. C) release of glutamate, ca2+, edema, o2 free radicals, degeneration occurs. Get ppl to hospital right away, if ischemic they can get tissue plasminogen activator (tpa) which will dissolve the clots and restore blood flow (within 3 hours)*
