HTHSCI 2H03 Lecture Notes - Lecture 3: Hyperglycemia, Adipose Tissue, Lipoprotein Lipase
29 Apr 2016
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Document Summary
Hyperlipidemia high lipid levels in the blood. Increases risk for atherosclerosis and coronary artery disease: plaque in the vessels that supply the heart, by controlling cholesterol levels, we can save the heart. Occurs predominately in men compared to non-menopausal women: there are some positive effects of estrogen. Associated with genetic alterations in fat metabolism and with excessive dietary intake of fats: it"s the extra cholesterol that"s a bad thing. After menopause (> 50 years of age). Moderate alcohol consumption increases good cholesterol blood levels: hdl! Adherence to proper diet may be sufficient, genetically linked alterations in lipid levels require pharmacotherapy. Triglycerides: account for 90% of total lipids in the body, important source of energy. Phospholipids: essential for the formation of cell membranes. Steroids: cholesterol, essential component of plasma membranes, building block for bile acids, vitamin d, cortisol, estrogen, and testosterone. Building blocks for essential proteins: liver can synthesize cholesterol, no need to obtain from diet.
