HTHSCI 2FF3 Lecture Notes - Mycobacterium Tuberculosis, Smallpox, Homeostasis
20 Feb 2020
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Document Summary
Immunology: principally concerned with the maintenance of homeostasis - protects us against p tumors, toxins, allergens etc. Serum antitoxins: recognition that if you get bitten by something and transfer it to someon they are protected. Primary immune response - lag phase (no present antibodies) then increas show up) Secondary immune response - previously seen, so no lag phase, immediate. Adaptive immune system has the ability to learn from previous expo. Antigen preventing cells: dendritic cells, macrophages, b cells. Performed when apcs interact with a t or b cell that is specific for a. Innate system (immediate + recruited) a. b. c. Activation of inflammatory mediator release: activati cytokines/chemokines, induce innate immune respo inflammation) Adaptive system: apcs are activated, migrate to lymph no. Influenza - rna virus that infects respiratory tract. Symptoms: productive cough (intrinsic barrier), generalize causing inflammatory symptoms), fever (inflammatory me. Dendritic cells (present) can detect double stranded rna u. Epithelial cells and macrophages produce interferons + cyto lungs)
