HTHSCI 1CC6 Lecture Notes - Lecture 13: Posterior Pituitary, Countercurrent Exchange, Aquaporin
25 Oct 2018
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In the medulla it is hyper concentrated solute movement: loop of henle is very specific going down only water moves. Allowed, coming up only solutes move water not allowed. Distributing prohibited | downloaded by arsen terzian (arsen98@gmail. com) lomoar cpsd|2151316. Released by the hypothalamus and posterior pituitary when there is an increase in osmolality of plasma and interstitial fluid From lecture: adh- allows aquaporins for water to be transported through. Adh- anti diuretic hormone- inhibits diuresis- or urine output. Adh makes the principal cells of the collecting ducts in the nephron more permeable to water by causing aquaporins- (channels for h20) to be inserted into their apical membranes. The amount of adh determines the number of aquaporins thus the amount of water that is absorbed and not excreted by the body. When the body is overhydrated, extracellular fluid osmolality decreases decreasing adh secretion by the posterior pituitary.
