PSYC 211 Lecture Notes - Lecture 33: Retina, Ovulation, Shift Work
16 Mar 2017
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Document Summary
Ach levels are high during waking hours and rem sleep and low during slow-wave sleep. Ach neurons responsible for rem sleep are found in pedunculopontine nucleus (ppt) and the laterodrosal tegmental nucleus (ldt); ppt and ldt are found within a region called the peribrachial area. Finding pattern of acetylcholinergic rem-on neuron in peribrachial area. Activity of single neuron in peribrachial area is related to sleep cycle. Rem-on cells fire only during rem sleep. The neuron increases its activity before the onset of rem sleep. Lesions of the peribrachial area reduce rem sleep. Neurons in the peribrachial area influence the thalamus, basal ganglia, the preoptic area, hippocampus, hypothalamus, cingulate cortex and brain stem nuclei that control eye movements. Ventrolateral periaqueductal grey matter (vlpag) contains rem-off cells. If animals are kept in constant darkness (or constant dim light), a brief period of bright light will reset their internal clock.
