PSYC 211 Lecture Notes - Lecture 67: Muscarinic Acetylcholine Receptor, Buprenorphine, Partial Agonist

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Not everyone is equally likely to become addicted to a drug. Both genetic and environmental factors play a role in determining a person"s likelihood of consuming drugs and of becoming dependent on them. Genetic factors: likelihood of taking and becoming addicted to any of a number of drugs. Specific factors: likelihood of taking and becoming addicted to a particular drug. Almost all heredity and genetic drug abuse studies have been made on twin pairs. Abusing any category of drug was associated with abusing drugs in all other categories. Abuse of every category except psychedelics: genetic factors peculiar to that category. Environment plays a strong role in influencing a person to try a drug and perhaps continue to use it recreationally, but. Genetics play a stronger role in determining whether the person becomes addicted. Goldman: measure heritability of various classes of addictive disorders. Heritability (h2) is the percentage of variability in a particular population that can be attributed to genetic variability.

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