PHGY 209 Lecture Notes - Lecture 16: Vascular Permeability, Kwashiorkor, Edema
3 May 2016
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Which coalesce to form larger lymphatic vessels, Which converge to form large lymphatic ducts, Which drain into the large veins in the chest. Volume returned by lymph drainage 3l (remember order of magnitude) Which proteins contribute the most to c. o. p. ? (colloidal osmotic pressure) The osmotic pressure of a solution depends on the number of osmotically active particles/unit volume. (not size configuration or charges) Each protein fraction exerts an osmotic pressure which is: directly related to its concentration in the plasma, inversely related to the molecular weight of that protein. Albumin contributes the most effect to the cop. Factors leading to edema (when isf compartment is increased: increase in hydrostatic pressure, decrease in cop, increase in capillary permeability, no lymphatic drainage. 55mm hg 25 cop = 30mm hg. 25mm hg 25 cop = 0mm hg. Normally there is very little protein in the isf.
