PHGY 209 Lecture Notes - Lecture 12: Pia Mater, Posterior Grey Column, Nmda Receptor
15 Apr 2018
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Document Summary
When these receptors are active, ca flows in, and ca is a signaling molecule this ca that flows in is a biochemical signal: the nmda can act as coincidence detector. Long term potentiation ltp is a model of synaptic plasticity. We can stimulate and action potential and record the epsp. We then stimulate the presynaptic axon so that theres a burst of action potentials, and more and more vesicles fuse. Each potential elicits an epsp, resulting in bigger and bigger depolarization of the postsynaptic cell and the mg will come out of, and ca will be triggered. Now the postsynaptic spine will trigger more ampa receptors to go into the membrane. Inhibitory synapses: gaba is the neurotransmitter released. The main inhibitory neurotransmitter in the brain is gaba. The postsynaptic receptor for the ipsp is the gabaa receptor, causing the ion channel in this receptor to open up. They are potentiating the inhibitory synapse in the brain.
