PHGY 209 Lecture Notes - Lecture 6: Vasodilation, Factor Vii, Blood Proteins
15 Apr 2018
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Lecture 6: the plasma proteins constitute most of the plasma solutes by weight. Their role in exerting an osmotic pressure that favors the absorption of ecf into capillaries is crucial. They can be classified into three groups: albumins- most abundant and synthesized by the liver, globulins, fibrinogen functions in clotting. Serum- plasma with fibrinogen and other proteins involved in clotting: cells normally do not take up plasma proteins, plasma proteins perform their functions in the plasma itself or in the isf. It is usefull to note that if there is high production of erythrocytes, there will be more reticulocytes in the blood: the average span of an erythrocyte is 120 days and they lack nuclei. Most destruction occurs in the liver or spleen: bilirubin= major breakdown product of hemoglobin. It is returned to plasma and gives it its yellowish colour: the body has a considerable store of iron, mainly in the liver, bound up in a protein called ferritin.
