PHAR 303 Lecture Notes - Lecture 19: Endocrine Disruptor, Rachel Carson, Thyroid
15 Feb 2018
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Midterm grades: average: 74. 4, std: 8. 9, max: 96, min: 50. The exam will have slightly more short answer questions than the midterm (~6, 3pts each) and there will be fewer type c and more type a questions. There will be ~15 questions taken from the poster presentation mcqs on the final. Begins in the brain higher brain centers will have input into the endocrine system. The hypothalamus will release small peptides (3-12 aas, except da) onto the pituitary. Figure 1 - the endocrine system: trh stimulates tsh to act on the thyroid (produce. T3 and t4: gnrh stimulates lh to act on the testis and ovary, dopamine negatively regulates prolactin to act on the testis and ovary, crh stimulates acth to act on the adrenal glands. The endocrine system is mostly regulated by negative feedback systems: e. g. as you produce more estradiol and testosterone, the pituitary will lower its production of lh (until steroid levels get too low again)
