PHAR 303 Lecture Notes - Lecture 3: Arsenic Poisoning, Chronic Toxicity, Arsenic
15 Feb 2018
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Found in rat poison, cigarette smoke, ground water, smelter air, and agricultural runoff. It has been used for many years as a drug: was used as far back as 2,400 years ago by hippocrates. Found mostly in agriculture and forestry, followed by industrial chemicals. Can cause with acute or chronic toxicity. 5 - correlation between arsenic in air and arsenic in urine: acute toxicity is generally with poisoning (suicide or homicide) This results in abdominal pain and collapse: chronic toxicity leads to skin cancer, as well and peripheral neuropathy with myelin loss, angiosarcoma of the liver, diabetes, and cardiovascular disease. The amount of arsenic in a person"s urine correlates with the amounts of arsenic in the air in their workplace. It has been found in ground water: it is viewed as fine in values less than 10 g/l (10 ppb) Most playgrounds in the city are contaminated with arsenic.
