PHAR 303 Lecture Notes - Lecture 2: Insulin-Like Growth Factor 1, High-Performance Liquid Chromatography, Pattern Recognition
22 Feb 2017
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Phar 303 lecture 2: assessment of exposure to toxicants (robaire) Canada has a domestic substances list for chemical management. It includes the most common substances likely to be produced in large volumes and that are most likely to be used in industry (and be on the market) Plan consists of 3 phases: cmp 1, 2, 3 phase 1 has the most data. Banning of bisphenol a and flame retardants were part of phase 1. The number of substances on the list decreases with each phase to focus action on a smaller number of chemicals. There have been no new chemicals added since 2005 even though hundreds of new ones have been introduced. Exposure = intensity x frequency x duration how much x how often x how long. The level of exposure will determine the response. As the exposure increases, the level of concern increases. Exposure ratings can be classified as % of oel (occupational exposure limit) of a substance.
