PHAR 301 Lecture Notes - Lecture 7: Jugular Venous Pressure, Hypokalemia, Volume Overload

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Phar 301 lecture 7: bowie (short notes) Congestive heart failure: chronic or acute state resulting from failure of the heart to meet oxygen demands of the body. We will explore variations in hemodynamics leading to an imbalance in supply and demand and ultimately the heart enlarges to compensate, irreparably damaging itself. Pulmonary embolism leads to acute heart failure. Underlying problems: left ventricular dysfxn failure to pump/hemodynamic model. Original explanation for heart failure (hf) bc the left side of the heart is responsible for supplying fresh blood into systemic circulation. Advent of drugs that increase the contractile force of the heart while waiting for surgery (inotropic: neuroendocrine activation. Compensatory mechanisms/actions involved in hf: if heart is not pumping well, the sympathetic ns stimulates and increase in hr. The same thing occurs in hf when oxygen demands are not met heart muscle enlarges but does not pump effectively.

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