PHAR 300 Lecture Notes - Lecture 1: Combined Oral Contraceptive Pill, Schizoaffective Disorder, Current Source
13 Sep 2016
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Midterm: oct 25, mc form 35% mid + 65% final. Relate basic science to drug effects, from cell to person. Histamine (natural): h1 blocker, cimetidine are blockers to histamine (do not need to rmb the chemical structures of the drugs) Cl- channel; ligand-gated ion channel in plasma membrane-cellular actions in molecular level. ?, toothpaste has f to prevent cavity formation; Food ex. plants, cheese gradients with bacterial or preservatives. Liver function: break down the chemicals, detox location in the body. Liver problems cause problems for detox, drug interactions. Useful drug in plants: ex. digitalis (plant, toxic to children) small dose for heart failure treatment; cancer drugs. Ex. venom, hormones: epipen for allergy containing epinephrine/adrenaline, human grown hormone for children growth; antibodies and cytokines for cancer; gene therapy. Immunotherapy: using antibodies and cytokines for autoimmune diseases and cancer. Treat specific diseases: hiv protease inhibitor to treat hiv. Understanding the virus: block the viral enzyme without effecting human body.
