PATH 300 Lecture Notes - Lecture 16: Gallstone, Angioma, Portal Venous System

• School: McGill University
• Department: Pathology
• Course: PATH 300
• Professor: Edith Zorychta

Document Summary

Large organ in the upper abdomen, below the diaphragm. Greatest regenerative ability (we can lose a lot of hepatocytes and if the structural integrity is still intact, it can completely recover but if the architecture is damage, regeneration is impaired => long term liver impairments) Large functional reserve -> portion can be damaged, enough left for us to still live. We have spare cells in most organ systems -> lose some and still be perfectly normal. Point at which our liver can no longer function adequately => infections and diseases can lead to severe illnesses and potentially death (nothing is completely resistant to injury) Disorders are common, symptoms are diverse because the liver does a lot of stuff. 60% from portal vein (blood draining the intestine -> goes to the liver rst) - > detoxi es, metabolises things before they get absorbed. 30% from hepatic artery (oxygenated blood) -> mingle inside the liver.