MIMM 465 Lecture Notes - Lecture 3: Cell Membrane, Hepatocyte, Interferon Type I

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A 26 year old nightclub dancer comes to hospital with a 1week history of low grade fever, malaise, nausea, abdominal pain, and pale colored diarrheal stools. At this point her boyfriend also noted that the whites of her eyes looked yellow. She no longer feels like smoking her customary pack per day of cigarettes. She denies use of illegal drugs but admits to drinking 5 8 glasses of wine each evening. Eyes looked yellow due to the overproduction of bilirubin or lack of excretion of body"s circulation. She has had a legal therapeutic abortion 1 month ago and has been taking a newly prescribed oral contraceptive since then. Oral contraceptive can have a side effect on liver and jaundice on some occasion. On physical examination she looks lethargic and obviously jaundiced. Hemoglobin (hgb, aka rbc), wbc counts and platelet counts are normal. But her bilirubin is 12 times elevated.

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