INDS 212 Lecture Notes - Lecture 61: Oligoclonal Band, Autoimmune Disease, Multiple Sclerosis
5 Jan 2019
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Why have lectures on ms: high prevalence in canada, 200 to 300 per 100,000; more women (2:1) to men, evidence for increasing prevalence. Increasing public awareness of the disease, so patients ask about this specifically: prevalence may be increasing even independent of these factors, most important cause of disability in young adults in canada. Immune mediated inflammatory disease of cns (not pns!) which causes demyelination and areas of sclerosis, permanent damage and eventual disability. Dissemination of disease in time and space : affects young adults: ms is diagnosed in kids and adults > 60, but most commonly in people between 18-50 resulting in axonal damage. Defined by recurrent attacks or relapses that happen over time causing. The evidence, although . not 100% clear, variety of things: pathology shows perivascular inflammation. We do not know yet what the implication is for ms. What is a typical clinical presentation: ms is characterized by dissemination of disease in time and space .
