INDS 211 Lecture Notes - Lecture 23: Corpus Luteum, Ectopic Pregnancy, Gestational Diabetes
2 Jan 2019
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Placenta: hcg, hpl, estrogens, progesterone: two main components: cytotrophoblast and synctiotrophoblast, maternal: maternal adrenal, maternal thyroid, fetal: adrenal. Importance of hcg test: pregnancy test: normal rate of rise: indicates fetal well-being. Highest levels in humans: rapid rise in 1st trimester: max @ 8-10 weeks of gestation. Maternal effects: glucose levels, lipolysis ( ffas), insulin action = If you"re diabetic and get pregnant, you will need to increase insulin provides fuel for fetus. Diabetogenic effect = causes gestational dm. because of this. Similarly, someone with gestational diabetes will also have gradually increasing insulin needs as time goes by: estrogens**: uterine blood flow/growth, prostaglandin synthesis, Prolactin secretion, softens ct, breast development (prl), water retention = effects important for maternal adaptation to pregnancy hcg: maintain corpus luteum, regulate e2 hpl: glucose-preserving (like gh), other metabolic roles breast development. Increasing steadily throughout pregnancy: source varies according to gestational age (see above) Estrogens cause: genital tract changes: uterus: 50g pre-preg 950g term.
