GEOG 203 Lecture Notes - Lecture 2: Creatine Kinase, Oxaloacetic Acid, Guanosine Triphosphate
7 Feb 2018
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Bioenergetics and its control 2: oxidative phosphorylation: Nadh + 1/2o2+ h+3adp + 3pi 3 atp + nad+ + h20. Inexhaustible substrate supply of atp we don"t have accumulation of metabolite exhaustion. Permits stabilization of cellular homeostasis: help to maintain intracellular concentrations of fatigue causing metabolites (ex: adp,pi,la,h) at levels that allow muscle power output to be sustained. Use potential energy available in reducing agents formed during the krebs cycle and glycolysis, nadh & fadh to rephosphorylate adp to atp. Prolonged atp supply for continued power output activities (ex: swimming) Relatively slow to initiate atp production (takes time to turn on ) Relies on glycolysis and its by products to activate its enzymes. Would like to match atp with oxidative phosphorylation but we have a kinetic response where we have to reach the steady state to obtain it o o. Unable to meet atp demand for very high power output activities (too slow)
