EDKP 447 Lecture Notes - Lecture 8: Cordotomy, Amplitude Modulation, Perineum

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Recovery of locomotion after chronic spinalization in the adult cat. Difference between cpg & motor programs * can incorporate cpg into motor programs. Central pattern generators cpg = 2 sources of input trigger: can function independently w/out, can receive input from brian that initiate & modulate. Higher drive from brain locomotor regions = clr/mlr/slr. Modulate cpg = descending command pathways from brain to sc that transmit stimulus for. Spinal plasticity = can improve cpg control of locomotion with training. Spinal cord can learn & memorize from constant triggered stimulus. Ex: cpg of lumbosacral spinal cord = circuitry for locomotion. Spinal cord cut so higher centers cannot influence lower spinal cord. *yet spinal cord produce rhythm without input from higher centers. Alternately stimulate flexor & extensor motor neurons in pattern. Recovery of locomotion after chronic spinalization in the adult cat - barbeau & rossignol, 1987: intact spinal cord.

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