EDKP 443 Lecture Notes - Lecture 23: Coronary Artery Disease, Relative Risk, Osteoporosis
Document Summary
Sample cohort study - harvard alumni health study. Focused on effects of exercise on coronary artery disease/ *data collected on lifestyle & health of men in 1962/1966/1977/1988/1993. Final assessment point = 11,894 men remained in study. C- provide insight into multiple effects of 1 single exposure. *how long chemical exposure to develop cancer/ length of. Identify group of people w/ exposure & follow-up to capture effect of exposure- chemical or policy. Harvard alumni study = role of physical activity om multiple. Cost = time for follow-up/financial $ pay personnel. *some disease outcomes too rare = not easy to find people exposure *voluntarily. Ex: people move away / die - lose participant always end up with fewer people. Start with high statistical power & ower lose statistical power when lose people. If study risk factor for rare condition *cohort bad = follow- Up people & wait but maybe nobody end up w/ condition: case-control studies - analytic design.