ANSC 312 Lecture Notes - Lecture 15: Rheumatic Fever, Type Iii Hypersensitivity, Anaphylaxis
15 Apr 2019
School
Department
Course
Professor
Document Summary
*please note that these notes complement the lecture slides. Lecture 15 hypersensitivity that keep encountering the antigens. Remember that the b cells secrete mediators when they are bound by antibodies. Mediators (prostaglandin and leukotrienes) directly act and their response is direct. Cytokines and chemokines have a slower response, because of their functions. If these mediators are released in the respiratory tract, it leads to anaphylactic shock, if the reaction lasts for a long time. Depending on the location of the reaction and the allergen (antigen) the antibodies come into contact with the antibodies leading to hypersensitivity, the manifestation will be more severe or not. Anaphylactic shock occurs when the allergic reaction occurs in the whole body. Normal hypersensitivity is usually localized in the respiratory tract or other system affected. If the igg can take care of the antigen (ex. Injection in blood), there is less chance that it will come into contact with ige and cause an intense reaction.
