ANSC 312 Lecture Notes - Lecture 7: Blood Vessel, Thrombosis, Endothelium
15 Apr 2019
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*please note that these notes complement the lecture slides. Thrombosis occurs when there is blood clotting, made by platelets, because they will encounter factors that are not present in normal conditions. Calcium) become active and act on other enzymes to activate them. The goal is to turn fibrinogen into fibrin with thrombin, leading to solid blood clot. The bleeding will stop, but that will also lead to inflammation. Then you have to get rid of the blood clot, because it can represent a threat. The clot could grow to the point it blocks the blood flow, or it will detach and float in blood until it blocks a smaller blood vessel. The major factor affecting thrombosis is the integrity of the endothelial cells. Polycythemia: too much blood cells in the blood (mainly rbc), either a real increase in rbc, or a decrease in fluids. Sometimes, part of it will detach and form an embolus leading to embolism.
