ANSC 312 Lecture Notes - Lecture 4: Thyrotropin-Releasing Hormone, Thyroid, Pituitary Gland
15 Apr 2019
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*please not that these notes complement the lecture slides. Lecture 4 disease at the cellular level. Hyperplasia is the increase in the number of cells in the tissue and it usually occurs with hypertrophy. Metaplasia: when tissues try to defend themselves to make cells that are more resistant. When the cells accumulate more water, they swell, and the organelles swell too. This is the first response to injury from the cells. Lipidosis is more common in cells that metabolite more lipids, as they already have more lipids in them (hepatocytes, myocytes) Cell swelling: more water (will stain more under microscope, accumulation of lipids, ribosomes detach from er, mitochondria swell, organelles start to fuse. At this stage the cell can still reverse back and be normal again: you know this because the condensation of the chromatin is quite normal. The condensation of the nucleus can be correlated with lower ph.
