ANSC 312 Lecture Notes - Lecture 10: Classical Swine Fever, Bovine Virus Diarrhea, Congenital Disorder

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Pestivirus, characterized by diarrhea, affects ruminants and swine. Noncytopathic establish consistent infections in cattle (90% of bvd isolates) Bvdv 1 and 2 because they have different antigens. Calves can get the disease through the placenta of the cow to the calf. The calves that contracted the disease while early in the gestation, will not develop an immune response and therefore will not have antibodies. Calves that get infected later on during the gestation, they will be born with the disease, but the calf will have antibodies for bvd and therefore the symptoms will be weaker and less important. Persistently infected calves are the ones that mainly give it to the cows of the herd and that is how the virus spreads. The main transmission mode is through direct contact. Sheep, swine, deer can also have the virus, and can transmit the disease to other. Integrating new animal that is infected, the whole herd will get the virus very rapidly.

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