BIOL 304 Lecture Notes - Lecture 1: Genetic Drift, Alcohol Dehydrogenase, Lactate Dehydrogenase
5 Mar 2018
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250th generation, stability, then another mutation etc: result: population is larger in size. Mendelian variation: aa or aa = homozygous, aa = heterozygous, genetic variation at this gene occurs when all individuals are not identical (not all aa or aa, genetic variation can be present within or among populations. Quantifying and comparing genetic variation: a- allele frequency: total number of one type of allele/total number of alleles (2x # of individuals, examples, 1. Example: assumer frequency of allele a1 is p=0. 6, frequency of a2 is q=0. 4. P = f(cid:396)e(cid:395)uency of (cid:862)a(cid:863) allele, (cid:395) = f(cid:396)e(cid:395)uency of (cid:862)a(cid:863) allele. P2 = frequency of homozygous genotype aa, 2pq = frequency of heterozygous genotype aa, q2 = frequency of homozygous genotype aa: final allele frequencies are expected to be the same when 5 conditions are met. Generalizing to more alleles per locus: p+q+r =1. Most traits are influenced by more than multiple mendelian genes environment, (p+q+r)2 = 1.
