BIOL 102 Lecture Notes - Lecture 17: Silent Mutation, Glycosidic Bond, Inosine
25 Jun 2016
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Wobble o recall there is a codon for every trna, but not a trna for every codon o some trnas can use more than one codon (some are able to recognize more than one codon) o wobble pairing the trna anticodon does not strictly obey base pairing rules o the 5" residue of the anticodon (which corresponds to the 3" residue of the codon) has some wobble it doesn"t always have to match up perfectly with the 3" residue of the codon. Frame shift mutation can result from an insertion or deletion and changes the reading frame from that point onwards: deletions or insertions that are multiples of three nucleotides do not change the reading frame, but merely delete amino acids from or insert amino acids into the peptide chain o chromosomal mutations changes that affect a large portions of a chromosome, often affecting many genes.
