PSYC-2606EL Lecture Notes - Lecture 9: Mercury Poisoning, Intellectual Disability, Subiculum
29 Dec 2017
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Document Summary
P-cells first, then golgi ii cells, basket and stellate, and granule. Differential cell proliferation, migration, growth, interaction between cells and necrosis. All neurons and glial cells originate from stem cells that line the ventricular matrices. Larger neuroblasts are formed first and migrate, smaller neurons form last. Most neurons are diploid, p-cells in hippocampus are tetraploid, glial are tetraploid. O(cid:374)(cid:272)e (cid:374)(cid:271)lasts (cid:373)igrate a(cid:374)d differe(cid:374)tiate the(cid:455) (cid:272)a(cid:374)"t divide, (cid:271)ut (cid:272)o(cid:374)ti(cid:374)ue to s(cid:455)(cid:374)thesize (cid:374)dna. Cajal-retzius cells, molecular layer of cerebral cortices. Rohan-beard (freud) cells, w/in spinal cord, atrophy before birth, migrational control of some parts of the brain. In cerebellum, transient external granule cells layer over the molecular layer, migrate down through p-cell layer into the granule layer. dendrites. Granule cell axons retrace these paths as they grow into the molecular layer and synapse w/ p-cells. Excessive adhesion between cohorts of migrating nblasts = source of ectopic tissue aggregates seen.
