PATH 3000 Lecture Notes - Lecture 31: Parathyroid Hormone, Parathyroid Carcinoma, Adenoma

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Path 3000 lecture 31 march 30, 2020 endocrine pathology ii. The kidney is also responsible for the reabsorption of calcium from the urine back into the bloodstream. If there is renal failure, then the reabsorption of calcium would be impaired and thus normal calcium level in the bloodstream would be difficult to maintain. Blood calcium level would be reduced, which would be sufficient to trigger the secretion of parathyroid hormones because their main function is to maintain calcium and phosphate levels. In the center shows the posterior view of the bilobed thyroid with 4 parathyroid glands. In parathyroid adenoma, one would typically see an enlarged parathyroid gland with the other glands remaining in normal size. If one of the parathyroid glands become cancerous, not only would the size of the gland be significantly enlarged, the cancer would start to invade into thyroid tissue or neighboring soft tissues or muscles.

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