NURS 2050 Lecture : Endocrine - Diabetes.docx
11 Apr 2013
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Classification: type i: result of pancreatic beta cell destruction. Requires insulin from the beginning, usually develops as a child. Autoimmune can also occur in adults: type ii: ranges from insulin resistance with relatively little insulin deficiency to predominantly secretory defect with insulin. Management: glucose levels: diet and exercise, insulin, oral hypoglycemics, lipid levels: cholesterol, blood pressure, lifestyle modifications: other risk factors (smoking, weight ) 5. 0-10. 0 (5. 0-8. 0 if a1c targets not being met) (2hrs after eating a meal) Glucagon, proglucagon insulin, c-peptide, proinsulin, amylin somatostatin gastrin pacreatic polypetide (pp) Insulin produced by the beta cells of islets of langerhans (stored as proinsulin) Dx of diabetes, note the trend, where bg is good, the insulin resistance is building, which leads to lower insulin levels. (this then leads to higher bg) After 0= decreasing ability of the pancreas to make insulin (not producing as much insulin) Insulin cannot be given po (gastric acid inactivates peptide)
