NEUR 3204 Lecture Notes - Lecture 7: Tryptophan Hydroxylase, Adenylyl Cyclase, Tryptophan
21 Feb 2020
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Psychodelics all bind to serotoninreceptors gq ex lsd. Importance ofseronin many normal behavioursappear deep on intactserotonin frt in brain can alterpersonality. Peripheral found alot in your gut in brain it is a neurotrans sleepfoodintake sexual behaviour. Tryptophan an essential ace thatcomesfrom your diet like mlk red meateggs etc ratelimitingstep is substratekryp availability. Tryp entryinto brain competes w largeneutral aa across bbb. 5 hi seasonalaffectivedisorder sad symptomcraving for carbohydrates becauseyou aretryingto make more 5 ht itmight be note depression l5 ht. Jb ex atkins keto diet no carb all protein lesstryp canget intoyour brain l 5 ht used as. Tryptophan hydroxylase trpoh rate limitingenzyme in 5 ht synthesis. 2tph1 outside of the brain your geneticmakeupdetermines nis of the 2typestrpoh. 5ht is made in the raphenuclei connections reach most of the brain when you givessris of sht in dorsal medialraphe area takes. In feedback mechanism a weeks seems to a trpoh thus a 54t.
