BIOL 2303 Lecture Notes - Lecture 21: Basic Reproduction Number, Tuberculosis, Rare Disease

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Study of the occurrence and distribution of disease. Epidemic: larger area but not global, high number, limited time frame. Exchange of bodily fluid, aerosols, respiratory infections. Typically seen with pathogens that are not able to survive outside the human body. Typically, only seen with pathogens that can survive or even multiply outside the human host. Via living, non-human carriers: vectors: most common vectors are insects, ticks in lyme disease, flease in plague, mosquitos in west nile virus. Via non-living, inanimate carries: formites: small scale, kids toys, pens, door handles, needles, vehicles: large scale, food, water. Localized, high incidence, over short period of time. Number of expected secondary transmissions from a single case. R0 > 1 likely to cause an outbreak or worse. R0 < 1 expected to die out on its own. Physical barriers to transmission (face masks, insect repellent, prophylactics.

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