KINE 2P09 Lecture Notes - Lecture 2: Particle Size, Membrane Transport Protein, Membrane Transport
11 Jun 2017
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2 factors: lipid solubility, particle size: lipid solubility. Polar molecules are hydrophilic, cannot pass through: particle size: if molecule is not lipid soluble it must be small enough to fit through a carrier protein. All molecules/ions constantly moving and bouncing off each other, will eventually even out over time. Moves from high to low concentration: electrical gradient. Ions= polar, must use channels to cross membrane. Aquaporins: always open, only allows water through. Water moves from area of high concentration to area of low concentration. Uses transporters (opening on one side only, only one specific molecule can bind to the binding site, which induces shape change, channel opens on other side of membrane) Secondary active transport: na binds to cotransporter, increases affinity for glucose, glucose binds, causes shape change, opens on inside of cell, na and glucose are released.
