BIOL 3P51 Lecture Notes - Lecture 9: Pax6, Population Genetics, Rhodopsin
27 Nov 2018
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26/11/2018: nuclear genome evolution, factors contributing to size & complexity of the nuclear genome, whole genome duplication, chromosome rearrangements, dna duplications-localized & dispersed to other locations. Cans still be through regulatory elements, through receptors, promoters. Chapter 12: population genetics: allele frequencies in populations, population- group of individuals of a single species that inhabit the same space at the same time, gene pool all alleles at a specific gene locus within the population. 1482: p^2 = 406/1482= 0. 274, 2pq= 744/1482=0. 502, q^2= 332/1482=0. 224, p=p^2 +pq -> use this over square rooting, p=0. 274*(0. 5*0. 502) =0. 525, q=1-p, q=0. 475. 26/11/2018: hardy-weinberg equilibrium, measure p and q, then calculate, p2, 2pq, q2. If calculated frequencies equal observed frequencies, then the population is in h-w equilibrium: genotype, lmlm, lmln, lnln, total, genotype, lmlm, p2, lmln, 2pq, lnln, q2. 0. 23: applications of h-w p = 0. 52, q = 0. 48.
