PHAR2210 Lecture Notes - Lecture 18: Royal Adelaide Hospital, World Health Organization, Adverse Drug Reaction
Document Summary
What is an adverse drug reaction: (adr): world health organisation: Harmful, unintended reactions to medicines that occur at doses normally used for treatment are called adverse drug reactions (adrs). : aust medicines handbook: Adverse effects are noxious and/or undesirable effects associated with the use of a drug at doses normally used. The process of identifying, monitoring, and effectively reducing adverse drug reactions. : note: normal doses can be hard to define in real populations, distinguishing an adr from a side effect can be difficult (latter may be useful sometime) Adrs: extend of the problem (usa): adrs rank among top ten causes of death, > 100,000 deaths/yr attributed to adrs. 2008 us data: the cost of adrs est. Increased by 90% from 2000 to 2008: adrs are a big liability for health care providers, and account for many lawsuits, due to rising rates of prescriptions and polypharmacy, these trends are likely to worsen.
