300889 Lecture Notes - Lecture 1: Respiratory Alkalosis, Respiratory Acidosis, Metabolic Alkalosis
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Any acid added to the blood can cause this, e. g. diabetes mallitus (due to excess ketone bodies) or lactate produced by tissues. (hco3: metabolic alkalosis > when hco3. Peripheral nerve injuries mechanisms: complete > like cutting with scissors. They are a compound structure at the end of a chromosome. With each cell division, the telomeres get shortened. They"re not replicated in adults, as it needs the enzyme telomerase, which is inactive in adults. Dna polymerase can"t engage in the start position, which then further division at some point becomes impossible. So this is one of the issues responsible for cellular ageing. Progeria a rare syndrome in children characterised by physical symptoms suggestive of premature old age. There is a synergistic relationship between telomere dysfunction and progerin production during the induction of cell senescence, providing mechanistic insight into how progerin may participate in the normal ageing process.