MBLG2972 Lecture Notes - Lecture 10: Inbreeding, Conservation Genetics, Heterosis

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MBLG2072
Genetics and Genomics
Monica Zanuttini !
460381099
Lecture 10 "Inbreeding
Defined as: assertive mating, lack of choice and self-fertilisation. !
Causes: allele frequencies to become erratic, dierentiation between subpopulations, uniformity
within subpopulations and an increase in homozygosity (expression of deleterious recessive
alleles). !
Coecient of inbreeding (F)!
Probability that two alleles are identical by descent in ONE individual.!
Self-fertilisation: !
Heterozygosity is halved in each generation. !
Common in plants. !
Splits a population into a series of homozygous lines. !
Coecient of relatedness (r): !
Probability that two alleles are identical by descent in TWO DIFFERENT individuals. !
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