EXSS2028 Lecture Notes - Lecture 6: Perfusion, Partial Pressure, Heart Failure

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Oxygen delivery to exercising muscles: gas exchange between alveoli & pulmonary capillary blood diffusion of o2 from the lung to the blood; Co2 goes to the lungs to be excreted: blood in arteries mitochondria cellular respiration co2 & atp released, co2 in vein heart lungs excreted, gas exchange occurs at the muscle level. Fick equation: co = hr x sv, a = arteriole, v = venous. Exercise physiology: lecture 6: vo2 is 20x that of the resting value in highly trained individuals (so therefore higher power output) 4: blood volume goes through 2 organs (kidneys & lungs) with each cardiac cycle, 0. 7s at rest allows diffusion of gas exchange from alveolar. What can go wrong to cause (cid:498)transformation(cid:499) to fail so pao2 & paco2. Inequality = va/q does not match (increased v on q: gas transport. Increasing metabolic rate increases the demand for o2.

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