EXSS2021 Lecture Notes - Lecture 7: Mediterranean Diet, Hypertriglyceridemia, Saturated Fat

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Iddm: b cells cannot produce insulin in the pancreas, so no insulin is released, causing an increase in glucose in the bloodstream (which cannot be used in the tissues for energy) Increased urine output, always thirsty, tired, lose weight. Insulin must be injected: younger onset, type 2 diabetes: Insulin is not released at the same level (little bit of insulin resistance: less glucose goes to the muscle/liver from the blood stream. Epidemiology & aetiology of type 1 diabetes: variation of prevalence may also depend on geographic location, genetics plays a role but in only 10% there is a clear family history. If the mother has diabetes, the risk for the child is 1-2%, if the father has diabetes, the risk for the child is 4-6% In an identical twin the risk is atleast 35: an autoimmune process destroys pancreatic islet beta cells.

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