HUBS1404 Lecture Notes - Lecture 22: Carbonic Acid, Anaerobic Respiration, Logarithmic Scale
19 Jul 2018
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Fix acids remain in body fluids until excreted (hcl, organic = la, ka) Buffers: weak acids and bases are important potential buffers. If ph rises - reaction proceeds to release more h+ (right) If ph falls - reaction proceeds to create more co2 (left: the chemical equilibrium between the weak acid and base has the net effect of buffering the solution. Body acids and bases: generally metabolic process create acids rather than bases, break down of proteins (eg release of phosphoric acid, anaerobic metabolism (la) Lipid metabolism (fa"s and ketone bodies: co2 transport as hco3. Ingestion of acids is a very minor contributor. The body"s buffering system: 3 systems act in a sequential manner to maintain acid-base balance, chemical buffers (immediate effect, respiratory system (minutes - only co2, renal system (hours - all other acids) Chemical buffers: they are "on-lotion" and in solution, so immediate ie no delay, 3 types, bicarbonate buffer system, phosphate buffer system, protein buffer system.
